Detection of glucose abnormalities in patients with acute coronary heart disease: study of reliable tools in clinical practice

التفاصيل البيبلوغرافية
العنوان: Detection of glucose abnormalities in patients with acute coronary heart disease: study of reliable tools in clinical practice
المؤلفون: M I, Del Olmo, J F, Merino-Torres, M, Argente, A, Ramos, M S, Navas, V, Campos, R, Cámara, A, Pérez-Lázaro
المصدر: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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بيانات النشر: SPRINGER, 2012.
سنة النشر: 2012
مصطلحات موضوعية: Adult, Aged, 80 and over, Glycated Hemoglobin, Male, Adolescent, Waist-Hip Ratio, Coronary Disease, Glucose Tolerance Test, Middle Aged, Body Mass Index, Young Adult, Glucose, Diabetes Mellitus, Type 2, Glucose Intolerance, Humans, Female, Prospective Studies, Acute Coronary Syndrome, Practice Patterns, Physicians', Aged
الوصف: To investigate the prevalence of glucose abnormalities in patients with acute coronary syndrome and to assess the reliability of certain clinical or analytical variables to predict a pathologic result of oral glucose tolerance test (OGTT) at 3 months from discharge.Prospective study of 102 patients admitted to the coronary care units. Patients were classified according to the American Diabetes Association criteria. Three months after discharge, an OGTT was performed to non-diabetic patients.Forty-six (45.1%) patients were identified as diabetic (5 previously undiagnosed) and 56 (54.9%) as non-diabetic. OGTT identified 22% of diabetes, 33% of impaired glucose tolerance, and 45% of normal glucose tolerance. Fasting glucose (r=0.55, p0.001), glycated hemoglobin (HbA1c) (r=0.46, p0.001), low HDL cholesterol (HDLc) levels (r=-0.34, p0.02), waist-hip ratio (r=0.45, p0.01), high systolic blood pressure (r=0.5, p0.01), and presence of acute myocardial infarction (r=0.46, p0.001) at admission resulted significant to predict a pathologic result of OGTT.Glucose abnormalities are frequent in acute coronary syndrome patients. Certain clinical and analytical markers at admission such as fasting glucose, HbA1c, HDL-c40 mg/dl, waist-hip ratio, and systolic blood pressure, are useful to recognize patients with a higher predisposition to present a pathologic result in OGTT at 3 months from discharge.
تدمد: 0391-4097
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9e37a589c50c388101d0d6ef4c75ea75
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=1203
حقوق: OPEN
رقم الأكسشن: edsair.pmid.dedup....9e37a589c50c388101d0d6ef4c75ea75
قاعدة البيانات: OpenAIRE