To summarize the research progress of interfacial tissue engineering in rotator cuff repair.The recent literature at home and abroad concerning interfacial tissue engineering in rotator cuff repair was analysed and summarized.Interfacial tissue engineering is to reconstruct complex and hierarchical interfacial tissues through a variety of methods to repair or regenerate damaged joints of different tissues. Interfacial tissue engineering in rotator cuff repair mainly includes seed cells, growth factors, biomaterials, oxygen concentration, and mechanical stimulation.The best strategy for rotator cuff healing and regeneration requires not only the use of biomaterials with gradient changes, but also the combination of seed cells, growth factors, and specific culture conditions (such as oxygen concentration and mechanical stimulation). However, the clinical transformation of the relevant treatment is still a very slow process.综述肩袖损伤修复的界面组织工程研究进展。.查阅近年国内外有关肩袖损伤修复的界面组织工程相关研究文献，并进行总结分析。.界面组织工程研究是通过多种方法重建复杂的、层次分明的界面组织，修复或再生受损的不同组织连接部位。肩袖损伤界面组织工程主要包括种子细胞、生长因子、生物材料、氧浓度和力学刺激等方面。.肩袖损伤愈合和再生的最佳策略不仅需要使用具有梯度变化的生物材料，还需要种子细胞、生长因子和特定培养条件（例如氧浓度和力学刺激）的结合，然而相应治疗手段的临床转化仍然是一个非常缓慢的过程。.
