تقرير
Dynamical Response of Nanomechanical Resonators to Biomolecular Interactions
| العنوان: | Dynamical Response of Nanomechanical Resonators to Biomolecular Interactions |
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| المؤلفون: | Eom, Kilho, Kwon, Tae Yun, Yoon, Dae Sung, Lee, Hong Lim, Kim, Tae Song |
| سنة النشر: | 2007 |
| المجموعة: | Condensed Matter Quantitative Biology |
| مصطلحات موضوعية: | Condensed Matter - Soft Condensed Matter, Quantitative Biology - Quantitative Methods |
| الوصف: | We studied the dynamical response of a nanomechanical resonator to biomolecular (e.g. DNA) adsorptions on a resonator's surface by using a theoretical model, which considers the Hamiltonian H such that the potential energy consists of elastic bending energy of a resonator and the potential energy for biomolecular interactions. It was shown that the resonant frequency shift of a resonator due to biomolecular adsorption depends on not only the mass of adsorbed biomolecules but also the biomolecular interactions. Specifically, for dsDNA adsorption on a resonator's surface, the resonant frequency shift is also dependent on the ionic strength of a solvent, implying the role of molecular interactions on the dynamic behavior of a resonator. This indicates that nanomechanical resonators may enable one to quantify the biomolecular mass, implying the enumeration of biomolecules, as well as gain insight into intermolecular interactions between adsorbed biomolecules on the surface. Comment: 17 page, 4 figures, accepted for publication at PRB. Physical Review B, accepted |
| نوع الوثيقة: | Working Paper |
| DOI: | 10.1103/PhysRevB.76.113408 |
| URL الوصول: | http://arxiv.org/abs/0706.3743 |
| رقم الأكسشن: | edsarx.0706.3743 |
| قاعدة البيانات: | arXiv |
| DOI: | 10.1103/PhysRevB.76.113408 |
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