Fluid limit theorems for stochastic hybrid systems with application to neuron models

التفاصيل البيبلوغرافية
العنوان: Fluid limit theorems for stochastic hybrid systems with application to neuron models
المؤلفون: Pakdaman, K., Thieullen, M., Wainrib, G.
سنة النشر: 2010
المجموعة: Mathematics
Quantitative Biology
مصطلحات موضوعية: Mathematics - Probability, Quantitative Biology - Neurons and Cognition, 60F05, 60F17, 60J75
الوصف: This paper establishes limit theorems for a class of stochastic hybrid systems (continuous deterministic dynamic coupled with jump Markov processes) in the fluid limit (small jumps at high frequency), thus extending known results for jump Markov processes. We prove a functional law of large numbers with exponential convergence speed, derive a diffusion approximation and establish a functional central limit theorem. We apply these results to neuron models with stochastic ion channels, as the number of channels goes to infinity, estimating the convergence to the deterministic model. In terms of neural coding, we apply our central limit theorems to estimate numerically impact of channel noise both on frequency and spike timing coding.
Comment: 42 pages, 4 figures
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/1001.2474
رقم الأكسشن: edsarx.1001.2474
قاعدة البيانات: arXiv