Modelling afferent nerve responses to bladder filling

التفاصيل البيبلوغرافية
العنوان: Modelling afferent nerve responses to bladder filling
المؤلفون: Argungu, Maryam, Bayram, Saziye, Brook, Bindi, Chakrabarti, Buddhapriya, Clayton, Richard H, Daly, Donna M, Dyson, Rosemary J, Holloway, Craig, Manhas, Varun, Naire, Shailesh, Shearer, Tom, Simitev, Radostin D.
سنة النشر: 2015
المجموعة: Quantitative Biology
مصطلحات موضوعية: Quantitative Biology - Tissues and Organs
الوصف: A sensation of fullness in the bladder is a regular experience, yet the mechanisms that act to generate this sensation remain poorly understood. This is an important issue because of the clinical problems that can result when this system does not function properly. The aim of the study group activity was to develop mathematical models that describe the mechanics of bladder filling, and how stretch modulates the firing rate of afferent nerves. Several models were developed, which were qualitatively consistent with experimental data obtained from a mouse model.
Comment: This report summarises the outcomes from a problem posed at the UK MMSG NC3R's \& POEMS Study Group meeting, 8--12 Sept 2014, Cambridge
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/1510.03119
رقم الأكسشن: edsarx.1510.03119
قاعدة البيانات: arXiv