تقرير
Proton radiography to improve proton radiotherapy: Simulation study at different proton beam energies
| العنوان: | Proton radiography to improve proton radiotherapy: Simulation study at different proton beam energies |
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| المؤلفون: | Biegun, A. K., Takatsu, Jun, van Goethem, M-J., van der Graaf, E. R., van Beuzekom, M., Visser, J., Brandenburg, S. |
| سنة النشر: | 2016 |
| المجموعة: | Physics (Other) |
| مصطلحات موضوعية: | Physics - Medical Physics |
| الوصف: | To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have systematic uncertainties in the calculated proton range in a patient of typically 3-4\% and even up to 10\% in region containing bone~\cite{USchneider1995,USchneider1996,WSchneider2000,GCirrone2007,HPaganetti2012,TPlautz2014,GLandry2013,JSchuemann2014}. As a consequence, part of a tumor may receive no dose, or a very high dose can be delivered in healthy ti\-ssues and organs at risks~(e.g. brain stem)~\cite{ACKnopf2013}. A transmission radiograph of high-energy protons measuring proton stopping powers directly will allow to reduce these uncertainties, and thus improve the quality of treatment. The best way to obtain a sufficiently accurate radiograph is by tracking individual protons traversing the phantom (patient)~\cite{GCirrone2007,TPlautz2014,VSipala2013}. In our simulations we have used an ideal position sensitive detectors measuring a single proton before and after a phantom, while the residual energy of a proton was detected by a BaF$_{2}$ crystal. To obtain transmission radiographs, diffe\-rent phantom materials have been irradiated with a 3x3~cm$^{2}$ scattered proton beam, with various beam energies. The simulations were done using the Geant4 simulation package~\cite{SAgostinelli2003}. In this study we focus on the simulations of the energy loss radiographs for various proton beam energies that are clinically available in proton radiotherapy. Comment: 6 pages, 6 figures, Presented at Jagiellonian Symposium on Fundamental and Applied Subatomic Physics, 7-12 June, 2015, Krak\'ow, Poland |
| نوع الوثيقة: | Working Paper |
| DOI: | 10.5506/APhysPolB.47.329 |
| URL الوصول: | http://arxiv.org/abs/1601.08074 |
| رقم الأكسشن: | edsarx.1601.08074 |
| قاعدة البيانات: | arXiv |
| DOI: | 10.5506/APhysPolB.47.329 |
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