تقرير
Estimation of neuronal interaction graph from spike train data
| العنوان: | Estimation of neuronal interaction graph from spike train data |
|---|---|
| المؤلفون: | Brochini, Ludmila, Galves, Antonio, Hodara, Pierre, Ost, Guilherme, Pouzat, Christophe |
| سنة النشر: | 2016 |
| المجموعة: | Quantitative Biology Statistics |
| مصطلحات موضوعية: | Quantitative Biology - Neurons and Cognition, Statistics - Applications |
| الوصف: | One of the main current issues in Neurobiology concerns the understanding of interrelated spiking activity among multineuronal ensembles and differences between stimulus-driven and spontaneous activity in neurophysiological experiments. Multi electrode array recordings that are now commonly used monitor neuronal activity in the form of spike trains from many well identified neurons. A basic question when analyzing such data is the identification of the directed graph describing "synaptic coupling" between neurons. In this article we deal with this matter working with a high quality multielectrode array recording dataset (Pouzat et al., 2015) from the first olfactory relay of the locust, $Schistocerca$ $americana$. From a mathematical point of view this paper presents two novelties. First we propose a procedure allowing to deal with the small sample sizes met in actual datasets. Moreover we address the sensitive case of partially observed networks. Our starting point is the procedure introduced in Duarte et al. (2016). We evaluate the performance of both original and improved procedures through simulation studies, which are also used for parameter tuning and for exploring the effect of recording only a small subset of the neurons of a network. |
| نوع الوثيقة: | Working Paper |
| URL الوصول: | http://arxiv.org/abs/1612.05226 |
| رقم الأكسشن: | edsarx.1612.05226 |
| قاعدة البيانات: | arXiv |
| الوصف غير متاح. |