Convolutional neural networks that teach microscopes how to image

التفاصيل البيبلوغرافية
العنوان: Convolutional neural networks that teach microscopes how to image
المؤلفون: Horstmeyer, Roarke, Chen, Richard Y., Kappes, Barbara, Judkewitz, Benjamin
سنة النشر: 2017
المجموعة: Computer Science
Physics (Other)
مصطلحات موضوعية: Computer Science - Computer Vision and Pattern Recognition, Computer Science - Artificial Intelligence, Computer Science - Learning, Physics - Optics
الوصف: Deep learning algorithms offer a powerful means to automatically analyze the content of medical images. However, many biological samples of interest are primarily transparent to visible light and contain features that are difficult to resolve with a standard optical microscope. Here, we use a convolutional neural network (CNN) not only to classify images, but also to optimize the physical layout of the imaging device itself. We increase the classification accuracy of a microscope's recorded images by merging an optical model of image formation into the pipeline of a CNN. The resulting network simultaneously determines an ideal illumination arrangement to highlight important sample features during image acquisition, along with a set of convolutional weights to classify the detected images post-capture. We demonstrate our joint optimization technique with an experimental microscope configuration that automatically identifies malaria-infected cells with 5-10% higher accuracy than standard and alternative microscope lighting designs.
Comment: 13 pages, 6 figures
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/1709.07223
رقم الأكسشن: edsarx.1709.07223
قاعدة البيانات: arXiv