تقرير
A model of electrical impedance tomography on peripheral nerves for a neural-prosthetic control interface
| العنوان: | A model of electrical impedance tomography on peripheral nerves for a neural-prosthetic control interface |
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| المؤلفون: | Hope, J., Vanholsbeeck, F., McDaid, A. |
| المصدر: | Hope, J., Vanholsbeeck, F., McDaid, A., A model of electrical impedance tomography implemented in nerve-cuff for neural-prosthetics control. Physiological Measurement, 2018 |
| سنة النشر: | 2017 |
| المجموعة: | Physics (Other) Quantitative Biology |
| مصطلحات موضوعية: | Quantitative Biology - Neurons and Cognition, Physics - Medical Physics |
| الوصف: | Objective: A model is presented to evaluate the viability of using electrical impedance tomography (EIT) with a nerve cuff to record neural activity in peripheral nerves. Approach: Established modelling approaches in neural-EIT are expanded on to be used, for the first time, on myelinated fibres which are abundant in mammalian peripheral nerves and transmit motor commands. Main results: Fibre impedance models indicate activity in unmyelinated fibres can be screened out using operating frequencies above 100 Hz. At 1 kHz and 10 mm electrode spacing, impedance magnitude of inactive intra-fascicle tissue and the fraction changes during neural activity are estimated to be 1,142 {\Omega}.cm and -8.8x10-4, respectively, with a transverse current, and 328 {\Omega}.cm & -0.30, respectively with a longitudinal current. We show that a novel EIT drive and measurement electrode pattern which utilises longitudinal current and longitudinal differential boundary voltage measurements could distinguish activity in different fascicles of a three-fascicle mammalian nerve using pseudo-experimental data synthesised to replicate real operating conditions. Significance: The results of this study provide an estimate of the transient change in impedance of intra-fascicle tissue during neural activity in mammalian nerve, and present a viable EIT electrode pattern, both of which are critical steps towards implementing EIT in a nerve cuff for neural prosthetics interfaces. Comment: 13 pages, 9 figures |
| نوع الوثيقة: | Working Paper |
| DOI: | 10.1088/1361-6579/aab73a |
| URL الوصول: | http://arxiv.org/abs/1711.04377 |
| رقم الأكسشن: | edsarx.1711.04377 |
| قاعدة البيانات: | arXiv |
| DOI: | 10.1088/1361-6579/aab73a |
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