تقرير
A phase field approach to trabecular bone remodeling
| العنوان: | A phase field approach to trabecular bone remodeling |
|---|---|
| المؤلفون: | Aland, S., Stenger, F., Müller, R., Kampschulte, M., Langheinrich, A. C., Khassawna, T. El, Heiß, C., Dreutsch, A., Voigt, A. |
| سنة النشر: | 2017 |
| المجموعة: | Mathematics Quantitative Biology |
| مصطلحات موضوعية: | Quantitative Biology - Tissues and Organs, Mathematics - Analysis of PDEs |
| الوصف: | We introduce a continuous modeling approach which combines elastic responds of the trabecular bone structure, the concentration of signaling molecules within the bone and a mechanism how this concentration at the bone surface is used for local bone formation and resorption. In an abstract setting bone can be considered as a shape changing structure. For similar problems in materials science phase field approximations have been established as an efficient computational tool. We adapt such an approach for trabecular bone remodeling. It allows for a smooth representation of the trabecular bone structure and drastically reduces computational costs if compared with traditional micro finite element approaches. We demonstrate the advantage of the approach within a minimal model. We quantitatively compare the results with established micro finite element approaches on simple geometries and consider the bone morphology within a bone segment obtained from $\mu$CT data of a sheep vertebra with realistic parameters. |
| نوع الوثيقة: | Working Paper |
| URL الوصول: | http://arxiv.org/abs/1711.07292 |
| رقم الأكسشن: | edsarx.1711.07292 |
| قاعدة البيانات: | arXiv |
| الوصف غير متاح. |