تقرير
Human-sized Magnetic Particle Imaging for Brain Applications
| العنوان: | Human-sized Magnetic Particle Imaging for Brain Applications |
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| المؤلفون: | Gräser, M., Thieben, F., Szwargulski, P., Werner, F., Gdaniec, N., Boberg, M., Griese, F., Möddel, M., Ludewig, P., van de Ven, D., Weber, O. M., Woywode, O., Gleich, B., Knopp, T. |
| سنة النشر: | 2018 |
| المجموعة: | Physics (Other) |
| مصطلحات موضوعية: | Physics - Medical Physics, Physics - Instrumentation and Detectors |
| الوصف: | Determining the brain perfusion is an important task for the diagnosis and treatment of vascular diseases such as occlusions and intracerebral haemorrhage. Even after successful diagnosis and treatment, there is a high risk of restenosis or rebleeding such that patients need intense and frequent attention in the days after treatment. Within this work, we will present a diagnostic tomographic imager that allows access to brain perfusion information quantitatively in short intervals. The imager is the first functional magnetic particle imaging device for brain imaging on a human-scale. It is highly sensitive and allows the detection of an iron concentration of 14.7 ng /ml (263 pmol\ml), which is the lowest iron concentration imaged by MPI so far. The imager is self-shielded and can be used in unshielded environments such as intensive care units. In combination with the low technical requirements this opens up a whole variety of possible medical applications and would allow monitoring possibilities on the stroke and intensive care units. Comment: 12 Pages (plus 5 pages methods) , 6 figures, 4 videos |
| نوع الوثيقة: | Working Paper |
| DOI: | 10.1038/s41467-019-09704-x |
| URL الوصول: | http://arxiv.org/abs/1810.07987 |
| رقم الأكسشن: | edsarx.1810.07987 |
| قاعدة البيانات: | arXiv |
| DOI: | 10.1038/s41467-019-09704-x |
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