تقرير
Photo-excitation production of medically interesting isomers using high-intensity {\gamma}-ray source
| العنوان: | Photo-excitation production of medically interesting isomers using high-intensity {\gamma}-ray source |
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| المؤلفون: | Pan, Wan-ting, Lan, Hao-yang, Ma, Zhi-guo, Zhu, Zhi-chao, Luo, Wen |
| المصدر: | Applied Radiation and Isotopes 168 (2021) 109534 |
| سنة النشر: | 2020 |
| المجموعة: | Nuclear Experiment Physics (Other) |
| مصطلحات موضوعية: | Nuclear Experiment, Physics - Applied Physics, Physics - Plasma Physics |
| الوصف: | Photon-induced nuclear excitation (i.e. photo-excitation) can be used for production of nuclear isomers, which have potential applications in astrophysics, energy storing, and medical diagnosis and treatment. This paper presents a feasibility study on production of four nuclear isomers ({99m}^Tc, {103m}^Rh and {113m, 115m}^In) using high-intensity {\gamma}-ray source based on laser-electron Compton scattering (LCS), for use in the medical diagnosis and treatment. The decay properties and the medical applications of these nuclear isomers were reviewed. The cross-section curves, simulated yields and activity of product of each photo-excitation process were calculated. The cutoff energy of LCS {\gamma}-ray beam is optimized by adjusting the electron energy in order to maximize the yields as well as the activities of photo-excitation products. It is found that the achievable activity of above-mentioned isomers can exceed 10 mCi for 6-hour target irradiation at an intensity of the order of 10^{13} {\gamma}/s. Such magnitude of activity satisfies the dose requirement of medical diagnosis. Our simulation results suggest the prospect of producing medically interesting isomers with photo-excitation using the state-of-art LCS {\gamma}-ray beam facility. Comment: 15 pages, 6 figures and 1 table |
| نوع الوثيقة: | Working Paper |
| DOI: | 10.1016/j.apradiso.2020.109534 |
| URL الوصول: | http://arxiv.org/abs/2007.02659 |
| رقم الأكسشن: | edsarx.2007.02659 |
| قاعدة البيانات: | arXiv |
| DOI: | 10.1016/j.apradiso.2020.109534 |
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