Using StyleGAN for Visual Interpretability of Deep Learning Models on Medical Images

التفاصيل البيبلوغرافية
العنوان: Using StyleGAN for Visual Interpretability of Deep Learning Models on Medical Images
المؤلفون: Schutte, Kathryn, Moindrot, Olivier, Hérent, Paul, Schiratti, Jean-Baptiste, Jégou, Simon
سنة النشر: 2021
المجموعة: Computer Science
مصطلحات موضوعية: Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Computer Vision and Pattern Recognition
الوصف: As AI-based medical devices are becoming more common in imaging fields like radiology and histology, interpretability of the underlying predictive models is crucial to expand their use in clinical practice. Existing heatmap-based interpretability methods such as GradCAM only highlight the location of predictive features but do not explain how they contribute to the prediction. In this paper, we propose a new interpretability method that can be used to understand the predictions of any black-box model on images, by showing how the input image would be modified in order to produce different predictions. A StyleGAN is trained on medical images to provide a mapping between latent vectors and images. Our method identifies the optimal direction in the latent space to create a change in the model prediction. By shifting the latent representation of an input image along this direction, we can produce a series of new synthetic images with changed predictions. We validate our approach on histology and radiology images, and demonstrate its ability to provide meaningful explanations that are more informative than GradCAM heatmaps. Our method reveals the patterns learned by the model, which allows clinicians to build trust in the model's predictions, discover new biomarkers and eventually reveal potential biases.
Comment: Accepted for oral session of Medical Imaging meets NeurIPS 2020 workshop: http://www.cse.cuhk.edu.hk/~qdou/public/medneurips2020/70_neurips2020_cameraready_opt.pdf
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2101.07563
رقم الأكسشن: edsarx.2101.07563
قاعدة البيانات: arXiv