Optimization of vaccination for COVID-19 in the midst of a pandemic

التفاصيل البيبلوغرافية
العنوان: Optimization of vaccination for COVID-19 in the midst of a pandemic
المؤلفون: Luo, Qi, Weightman, Ryan, McQuade, Sean T., Diaz, Mateo, Trélat, Emmanuel, Barbour, William, Work, Dan, Samaranayake, Samitha, Piccoli, Benedetto
سنة النشر: 2022
المجموعة: Mathematics
Quantitative Biology
مصطلحات موضوعية: Quantitative Biology - Populations and Evolution, Mathematics - Optimization and Control
الوصف: During the Covid-19 pandemic a key role is played by vaccination to combat the virus. There are many possible policies for prioritizing vaccines, and different criteria for optimization: minimize death, time to herd immunity, functioning of the health system. Using an age-structured population compartmental finite-dimensional optimal control model, our results suggest that the eldest to youngest vaccination policy is optimal to minimize deaths. Our model includes the possible infection of vaccinated populations. We apply our model to real-life data from the US Census for New Jersey and Florida, which have a significantly different population structure. We also provide various estimates of the number of lives saved by optimizing the vaccine schedule and compared to no vaccination.
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2203.09502
رقم الأكسشن: edsarx.2203.09502
قاعدة البيانات: arXiv