Encapsulated bacteria deform lipid vesicles into flagellated swimmers

التفاصيل البيبلوغرافية
العنوان: Encapsulated bacteria deform lipid vesicles into flagellated swimmers
المؤلفون: Nagard, Lucas Le, Brown, Aidan T., Dawson, Angela, Martinez, Vincent A., Poon, Wilson C. K., Staykova, Margarita
المصدر: Proceedings of the National Academy of Sciences, 119(34), e2206096119 (2022)
سنة النشر: 2022
المجموعة: Condensed Matter
Physics (Other)
مصطلحات موضوعية: Condensed Matter - Soft Condensed Matter, Physics - Biological Physics
الوصف: We study a synthetic system of motile Escherichia coli bacteria encapsulated inside giant lipid vesicles. Forces exerted by the bacteria on the inner side of the membrane are sufficient to extrude membrane tubes filled with one or several bacteria. We show that a physical coupling between the membrane tube and the flagella of the enclosed cells transforms the tube into an effective helical flagellum propelling the vesicle. We develop a simple theoretical model to estimate the propulsive force from the speed of the vesicles, and demonstrate the good efficiency of this coupling mechanism. Together, these results point to design principles for conferring motility to synthetic cells.
Comment: 22 pages, 12 figures
نوع الوثيقة: Working Paper
DOI: 10.1073/pnas.2206096119
URL الوصول: http://arxiv.org/abs/2204.03721
رقم الأكسشن: edsarx.2204.03721
قاعدة البيانات: arXiv