Unsupervised Probabilistic Models for Sequential Electronic Health Records

التفاصيل البيبلوغرافية
العنوان: Unsupervised Probabilistic Models for Sequential Electronic Health Records
المؤلفون: Kaplan, Alan D., Greene, John D., Liu, Vincent X., Ray, Priyadip
سنة النشر: 2022
المجموعة: Computer Science
Quantitative Biology
مصطلحات موضوعية: Computer Science - Machine Learning, Quantitative Biology - Quantitative Methods
الوصف: We develop an unsupervised probabilistic model for heterogeneous Electronic Health Record (EHR) data. Utilizing a mixture model formulation, our approach directly models sequences of arbitrary length, such as medications and laboratory results. This allows for subgrouping and incorporation of the dynamics underlying heterogeneous data types. The model consists of a layered set of latent variables that encode underlying structure in the data. These variables represent subject subgroups at the top layer, and unobserved states for sequences in the second layer. We train this model on episodic data from subjects receiving medical care in the Kaiser Permanente Northern California integrated healthcare delivery system. The resulting properties of the trained model generate novel insight from these complex and multifaceted data. In addition, we show how the model can be used to analyze sequences that contribute to assessment of mortality likelihood.
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2204.07292
رقم الأكسشن: edsarx.2204.07292
قاعدة البيانات: arXiv