Inference of Stochastic Disease Transmission Models Using Particle-MCMC and a Gradient Based Proposal

التفاصيل البيبلوغرافية
العنوان: Inference of Stochastic Disease Transmission Models Using Particle-MCMC and a Gradient Based Proposal
المؤلفون: Rosato, Conor, Harris, John, Panovska-Griffiths, Jasmina, Maskell, Simon
سنة النشر: 2022
المجموعة: Statistics
مصطلحات موضوعية: Statistics - Applications
الوصف: State-space models have been widely used to model the dynamics of communicable diseases in populations of interest by fitting to time-series data. Particle filters have enabled these models to incorporate stochasticity and so can better reflect the true nature of population behaviours. Relevant parameters such as the spread of the disease, $R_t$, and recovery rates can be inferred using Particle MCMC. The standard method uses a Metropolis-Hastings random-walk proposal which can struggle to reach the stationary distribution in a reasonable time when there are multiple parameters. In this paper we obtain full Bayesian parameter estimations using gradient information and the No U-Turn Sampler (NUTS) when proposing new parameters of stochastic non-linear Susceptible-Exposed-Infected-Recovered (SEIR) and SIR models. Although NUTS makes more than one target evaluation per iteration, we show that it can provide more accurate estimates in a shorter run time than Metropolis-Hastings.
Comment: FUSION 2022: 25th International Conference on Information Fusion (FUSION 2022), 8 Pages, 16 images
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2205.07356
رقم الأكسشن: edsarx.2205.07356
قاعدة البيانات: arXiv