A Multivariate Point Process Model for Simultaneously Recorded Neural Spike Trains

التفاصيل البيبلوغرافية
العنوان: A Multivariate Point Process Model for Simultaneously Recorded Neural Spike Trains
المؤلفون: Ramezan, Reza, Chen, Meixi, Lysy, Martin, Marriott, Paul
سنة النشر: 2022
مصطلحات موضوعية: Statistics - Methodology, Quantitative Biology - Neurons and Cognition
الوصف: The current state-of-the-art in neurophysiological data collection allows for simultaneous recording of tens to hundreds of neurons, for which point processes are an appropriate statistical modelling framework. However, existing point process models lack multivariate generalizations which are both flexible and computationally tractable. This paper introduces a multivariate generalization of the Skellam process with resetting (SPR), a point process tailored to model individual neural spike trains. The multivariate SPR (MSPR) is biologically justified as it mimics the process of neural integration. Its flexible dependence structure and a fast parameter estimation method make it well-suited for the analysis of simultaneously recorded spike trains from multiple neurons. The strengths and weaknesses of the MSPR are demonstrated through simulation and analysis of experimental data.
Comment: 6 pages, 1 figure
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2206.09903
رقم الأكسشن: edsarx.2206.09903
قاعدة البيانات: arXiv