Neural source/sink phase connectivity in developmental dyslexia by means of interchannel causality

التفاصيل البيبلوغرافية
العنوان: Neural source/sink phase connectivity in developmental dyslexia by means of interchannel causality
المؤلفون: RodrÍguez-RodrÍguez, I., Ortiz, A., Gallego-Molina, N. J., Formoso, M. A., Woo, W. L.
سنة النشر: 2023
المجموعة: Computer Science
Quantitative Biology
مصطلحات موضوعية: Quantitative Biology - Neurons and Cognition, Computer Science - Artificial Intelligence
الوصف: While the brain connectivity network can inform the understanding and diagnosis of developmental dyslexia, its cause-effect relationships have not yet enough been examined. Employing electroencephalography signals and band-limited white noise stimulus at 4.8 Hz (prosodic-syllabic frequency), we measure the phase Granger causalities among channels to identify differences between dyslexic learners and controls, thereby proposing a method to calculate directional connectivity. As causal relationships run in both directions, we explore three scenarios, namely channels' activity as sources, as sinks, and in total. Our proposed method can be used for both classification and exploratory analysis. In all scenarios, we find confirmation of the established right-lateralized Theta sampling network anomaly, in line with the temporal sampling framework's assumption of oscillatory differences in the Theta and Gamma bands. Further, we show that this anomaly primarily occurs in the causal relationships of channels acting as sinks, where it is significantly more pronounced than when only total activity is observed. In the sink scenario, our classifier obtains 0.84 and 0.88 accuracy and 0.87 and 0.93 AUC for the Theta and Gamma bands, respectively.
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2301.00552
رقم الأكسشن: edsarx.2301.00552
قاعدة البيانات: arXiv