تقرير
Getting the phase consistent: The importance of phase description in balanced steady-state free precession MRI of multicompartment systems
| العنوان: | Getting the phase consistent: The importance of phase description in balanced steady-state free precession MRI of multicompartment systems |
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| المؤلفون: | Plähn, Nils M. J., Poli, Simone, Peper, Eva S., Açikgöz, Berk C., Kreis, Roland, Ganter, Carl, Bastiaansen, Jessica A. M. |
| سنة النشر: | 2023 |
| المجموعة: | Physics (Other) |
| مصطلحات موضوعية: | Physics - Medical Physics |
| الوصف: | Purpose: Determine the correct mathematical phase description for balanced steady-state free precession (bSSFP) signals in multicompartment systems. Theory and Methods: Based on published bSSFP signal models, two distinct phase descriptions can be formulated: one predicting the presence and the other predicting the absence of destructive interference effects in multicompartment systems. Numerical simulations of bSSFP signals of water and acetone were performed to evaluate the predictions of these two distinct phase descriptions. For experimental validation, bSSFP profiles were measured at 3T using phase-cycled bSSFP acquisitions performed in a phantom containing mixtures of water and acetone, which replicates a system with two signal components. Localized single voxel MRS was performed at 7T to determine the relative chemical-shift of the acetone-water mixtures. Results: Based on the choice of phase description, the simulated bSSFP profiles of water-acetone mixtures varied significantly, either displaying or lacking destructive interference effects, as predicted theoretically. In phantom experiments, destructive interference was consistently observed in the measured bSSFP profiles of water-acetone mixtures, an observation which excludes the phase description that predicts an absence of destructive interference. The connection between the choice of phase description and predicted observation enables an unambiguous experimental identification of the correct phase description for multicompartment bSSFP profiles, which is consistent with Bloch equations. Conclusion: The study emphasizes that consistent phase descriptions are crucial for accurately describing multi-compartment bSSFP signals, as incorrect phase descriptions result in erroneous predictions. Comment: Submitted to Magn. Reson. Med |
| نوع الوثيقة: | Working Paper |
| URL الوصول: | http://arxiv.org/abs/2302.12548 |
| رقم الأكسشن: | edsarx.2302.12548 |
| قاعدة البيانات: | arXiv |
| الوصف غير متاح. |