Towards Tumour Graph Learning for Survival Prediction in Head & Neck Cancer Patients

التفاصيل البيبلوغرافية
العنوان: Towards Tumour Graph Learning for Survival Prediction in Head & Neck Cancer Patients
المؤلفون: Muller, Angel Victor Juanco, Mota, Joao F. C., Goatman, Keith A., Hoogendoorn, Corne
سنة النشر: 2023
المجموعة: Computer Science
مصطلحات موضوعية: Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Computer Vision and Pattern Recognition, Computer Science - Machine Learning
الوصف: With nearly one million new cases diagnosed worldwide in 2020, head \& neck cancer is a deadly and common malignity. There are challenges to decision making and treatment of such cancer, due to lesions in multiple locations and outcome variability between patients. Therefore, automated segmentation and prognosis estimation approaches can help ensure each patient gets the most effective treatment. This paper presents a framework to perform these functions on arbitrary field of view (FoV) PET and CT registered scans, thus approaching tasks 1 and 2 of the HECKTOR 2022 challenge as team \texttt{VokCow}. The method consists of three stages: localization, segmentation and survival prediction. First, the scans with arbitrary FoV are cropped to the head and neck region and a u-shaped convolutional neural network (CNN) is trained to segment the region of interest. Then, using the obtained regions, another CNN is combined with a support vector machine classifier to obtain the semantic segmentation of the tumours, which results in an aggregated Dice score of 0.57 in task 1. Finally, survival prediction is approached with an ensemble of Weibull accelerated failure times model and deep learning methods. In addition to patient health record data, we explore whether processing graphs of image patches centred at the tumours via graph convolutions can improve the prognostic predictions. A concordance index of 0.64 was achieved in the test set, ranking 6th in the challenge leaderboard for this task.
Comment: Published by Springer as part of the HECKTOR 2022 challenge proccedings https://link.springer.com/chapter/10.1007/978-3-031-27420-6_18
نوع الوثيقة: Working Paper
DOI: 10.1007/978-3-031-27420-6_18
URL الوصول: http://arxiv.org/abs/2304.08106
رقم الأكسشن: edsarx.2304.08106
قاعدة البيانات: arXiv
الوصف
DOI:10.1007/978-3-031-27420-6_18