In this paper, we prove global-in-time existence of strong solutions to a class of fractional parabolic reaction-diffusion systems posed in a bounded domain of $\mathbb{R}^N$. The nonlinear reactive terms are assumed to satisfy natural structure conditions which provide non-negativity of the solutions and uniform control of the total mass. The diffusion operators are of type $u_i\mapsto d_i(-\Delta)^s u_i$ where $0