General-Purpose vs. Domain-Adapted Large Language Models for Extraction of Structured Data from Chest Radiology Reports

التفاصيل البيبلوغرافية
العنوان: General-Purpose vs. Domain-Adapted Large Language Models for Extraction of Structured Data from Chest Radiology Reports
المؤلفون: Dhanaliwala, Ali H., Ghosh, Rikhiya, Karn, Sanjeev Kumar, Ullaskrishnan, Poikavila, Farri, Oladimeji, Comaniciu, Dorin, Kahn, Charles E.
سنة النشر: 2023
المجموعة: Computer Science
مصطلحات موضوعية: Computer Science - Computation and Language, Electrical Engineering and Systems Science - Image and Video Processing
الوصف: Radiologists produce unstructured data that can be valuable for clinical care when consumed by information systems. However, variability in style limits usage. Study compares system using domain-adapted language model (RadLing) and general-purpose LLM (GPT-4) in extracting relevant features from chest radiology reports and standardizing them to common data elements (CDEs). Three radiologists annotated a retrospective dataset of 1399 chest XR reports (900 training, 499 test) and mapped to 44 pre-selected relevant CDEs. GPT-4 system was prompted with report, feature set, value set, and dynamic few-shots to extract values and map to CDEs. Output key:value pairs were compared to reference standard at both stages and an identical match was considered TP. F1 score for extraction was 97% for RadLing-based system and 78% for GPT-4 system. F1 score for mapping was 98% for RadLing and 94% for GPT-4; difference was statistically significant (P<.001). RadLing's domain-adapted embeddings were better in feature extraction and its light-weight mapper had better f1 score in CDE assignment. RadLing system also demonstrated higher capabilities in differentiating between absent (99% vs 64%) and unspecified (99% vs 89%). RadLing system's domain-adapted embeddings helped improve performance of GPT-4 system to 92% by giving more relevant few-shot prompts. RadLing system offers operational advantages including local deployment and reduced runtime costs.
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2311.17213
رقم الأكسشن: edsarx.2311.17213
قاعدة البيانات: arXiv