Shapley Values-enabled Progressive Pseudo Bag Augmentation for Whole Slide Image Classification

التفاصيل البيبلوغرافية
العنوان: Shapley Values-enabled Progressive Pseudo Bag Augmentation for Whole Slide Image Classification
المؤلفون: Yan, Renao, Sun, Qiehe, Jin, Cheng, Liu, Yiqing, He, Yonghong, Guan, Tian, Chen, Hao
سنة النشر: 2023
المجموعة: Computer Science
مصطلحات موضوعية: Computer Science - Computer Vision and Pattern Recognition
الوصف: In computational pathology, whole slide image (WSI) classification presents a formidable challenge due to its gigapixel resolution and limited fine-grained annotations. Multiple instance learning (MIL) offers a weakly supervised solution, yet refining instance-level information from bag-level labels remains complex. While most of the conventional MIL methods use attention scores to estimate instance importance scores (IIS) which contribute to the prediction of the slide labels, these often lead to skewed attention distributions and inaccuracies in identifying crucial instances. To address these issues, we propose a new approach inspired by cooperative game theory: employing Shapley values to assess each instance's contribution, thereby improving IIS estimation. The computation of the Shapley value is then accelerated using attention, meanwhile retaining the enhanced instance identification and prioritization. We further introduce a framework for the progressive assignment of pseudo bags based on estimated IIS, encouraging more balanced attention distributions in MIL models. Our extensive experiments on CAMELYON-16, BRACS, and TCGA-LUNG datasets show our method's superiority over existing state-of-the-art approaches, offering enhanced interpretability and class-wise insights. We will release the code upon acceptance.
Comment: submitted to IEEE TRANSACTIONS ON MEDICAL IMAGING
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2312.05490
رقم الأكسشن: edsarx.2312.05490
قاعدة البيانات: arXiv