Agent-Based Modeling of C. Difficile Spread in Hospitals: Assessing Contribution of High-Touch vs. Low-Touch Surfaces and Inoculations' Containment Impact

التفاصيل البيبلوغرافية
العنوان: Agent-Based Modeling of C. Difficile Spread in Hospitals: Assessing Contribution of High-Touch vs. Low-Touch Surfaces and Inoculations' Containment Impact
المؤلفون: Abdidizaji, Sina, Yalabadi, Ali Khodabandeh, Yazdani-Jahromi, Mehdi, Garibay, Ozlem Ozmen, Garibay, Ivan
سنة النشر: 2024
المجموعة: Computer Science
مصطلحات موضوعية: Computer Science - Multiagent Systems
الوصف: Health issues and pandemics remain paramount concerns in the contemporary era. Clostridioides Difficile Infection (CDI) stands out as a critical healthcare-associated infection with global implications. Effectively understanding the mechanisms of infection dissemination within healthcare units and hospitals is imperative to implement targeted containment measures. In this study, we address the limitations of prior research by Sulyok et al., where they delineated two distinct categories of surfaces as high-touch and low-touch fomites, and subsequently evaluated the viral spread contribution of each surface utilizing mathematical modeling and Ordinary Differential Equations (ODE). Acknowledging the indispensable role of spatial features and heterogeneity in the modeling of hospital and healthcare settings, we employ agent-based modeling to capture new insights. By incorporating spatial considerations and heterogeneous patients, we explore the impact of high-touch and low-touch surfaces on contamination transmission between patients. Furthermore, the study encompasses a comprehensive assessment of various cleaning protocols, with differing intervals and detergent cleaning efficacies, in order to identify the most optimal cleaning strategy and the most important factor amidst the array of alternatives. Our results indicate that, among various factors, the frequency of cleaning intervals is the most critical element for controlling the spread of CDI in a hospital environment.
Comment: Accepted and presented at the Computational Social Science Society of the Americas Conference (CSS 2023)
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2401.11656
رقم الأكسشن: edsarx.2401.11656
قاعدة البيانات: arXiv