تقرير
Relaxation Dynamics in Persistent Epithelial Tissues
| العنوان: | Relaxation Dynamics in Persistent Epithelial Tissues |
|---|---|
| المؤلفون: | Li, Meng-Yuan, Li, Yan-Wei |
| سنة النشر: | 2024 |
| المجموعة: | Condensed Matter |
| مصطلحات موضوعية: | Condensed Matter - Soft Condensed Matter |
| الوصف: | Cell monolayers and epithelial tissues display slow dynamics during the liquid-glass transitions, a phenomenon with direct relevance to embryogenesis, tumor metastases, and wound healing. In active cells, persistent motion and cell deformation compete, significantly influencing relaxation dynamics. Here, we numerically construct the liquid-glass transition phase diagram for two-dimensional polydisperse persistent cells. We employ cage-relative measures and conduct extensive simulations to eliminate the influence of system size effects. These effects arise from long-wavelength fluctuations in nearly equilibrated cells and a combination of long-wavelength fluctuations and non-equilibrium effects in highly persistent cells. Our study unveils distinctive intermittent dynamics associated with intermittent T1 transitions in highly persistent cells, where the velocity correlates over space with a characteristic length $\xi$. The $\alpha$ relaxation time exhibits a universal power-law dependence on the irreversible T1 transition rate, $\Gamma_{\rm{T1}}^{\rm irr}$, multiplied by ${\rm exp}(\xi)$. Here, $\xi$ vanishes in nearly equilibrated cells, and $\Gamma_{\rm{T1}}^{\rm irr}$ diminishes towards the mode-coupling glass transition point. Comment: 6 pages, 4 figures |
| نوع الوثيقة: | Working Paper |
| URL الوصول: | http://arxiv.org/abs/2401.13375 |
| رقم الأكسشن: | edsarx.2401.13375 |
| قاعدة البيانات: | arXiv |
| الوصف غير متاح. |