ReStainGAN: Leveraging IHC to IF Stain Domain Translation for in-silico Data Generation

التفاصيل البيبلوغرافية
العنوان: ReStainGAN: Leveraging IHC to IF Stain Domain Translation for in-silico Data Generation
المؤلفون: Winter, Dominik, Triltsch, Nicolas, Plewa, Philipp, Rosati, Marco, Padel, Thomas, Hill, Ross, Schick, Markus, Brieu, Nicolas
سنة النشر: 2024
المجموعة: Computer Science
مصطلحات موضوعية: Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Artificial Intelligence, Computer Science - Computer Vision and Pattern Recognition, Computer Science - Machine Learning, I.2.10, J.3, I.4.6
الوصف: The creation of in-silico datasets can expand the utility of existing annotations to new domains with different staining patterns in computational pathology. As such, it has the potential to significantly lower the cost associated with building large and pixel precise datasets needed to train supervised deep learning models. We propose a novel approach for the generation of in-silico immunohistochemistry (IHC) images by disentangling morphology specific IHC stains into separate image channels in immunofluorescence (IF) images. The proposed approach qualitatively and quantitatively outperforms baseline methods as proven by training nucleus segmentation models on the created in-silico datasets.
Comment: 4 pages, 1 figure
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2403.06545
رقم الأكسشن: edsarx.2403.06545
قاعدة البيانات: arXiv