We present design methods and insights for CO2 capture, transport, and storage systems for clusters of industrial facilities, with a case-study focus on the state of Louisiana. Our analytical framework includes: (1) evaluating the scale and concentration of capturable CO2 emissions at individual facilities for the purpose of estimating the cost of CO2 capture retrofits, (2) a screening method to identify potential CO2 storage sites and estimate their storage capacities, injectivities, and costs; and (3) an approach for cost-minimized design of pipeline infrastructure connecting CO2 capture plants with storage sites that considers land use patterns, existing rights-of-way, demographics, and a variety of social and environmental justice factors. In applying our framework to Louisiana, we estimate up to 50 million tCO2/y of industrial emissions (out of today's total emissions of 130 MtCO2/y) can be captured at under 100 USD/tCO2, and up to 100 MtCO2/y at under 120 USD/tCO2. We identified 98 potential storage sites with estimated aggregate total injectivity between 330 and 730 MtCO2/yr and storage costs ranging from 8 to 17 USD/tCO2. We find dramatic reductions in the aggregate pipeline length and CO2 transport cost per tonne when groups of capture plants share pipeline infrastructure rather than build dedicated single-user pipelines. Smaller facilities (emitting less than 1 MtCO2/y), which account for a quarter of Louisiana's industrial emissions, see the largest transport cost benefits from sharing of infrastructure. Pipeline routes designed to avoid disadvantaged communities (social and environmental justice) so as not to reinforce historical practices of disenfranchisement involve only modestly higher pipeline lengths and costs.