ResNCT: A Deep Learning Model for the Synthesis of Nephrographic Phase Images in CT Urography

التفاصيل البيبلوغرافية
العنوان: ResNCT: A Deep Learning Model for the Synthesis of Nephrographic Phase Images in CT Urography
المؤلفون: Gardezi, Syed Jamal Safdar, Aronson, Lucas, Wawrzyn, Peter, Yu, Hongkun, Abel, E. Jason, Shapiro, Daniel D., Lubner, Meghan G., Warner, Joshua, Toia, Giuseppe, Mao, Lu, Tiwari, Pallavi, Wentland, Andrew L.
سنة النشر: 2024
المجموعة: Computer Science
Physics (Other)
مصطلحات موضوعية: Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Artificial Intelligence, Physics - Medical Physics, eess.IV, J.3
الوصف: Purpose: To develop and evaluate a transformer-based deep learning model for the synthesis of nephrographic phase images in CT urography (CTU) examinations from the unenhanced and urographic phases. Materials and Methods: This retrospective study was approved by the local Institutional Review Board. A dataset of 119 patients (mean $\pm$ SD age, 65 $\pm$ 12 years; 75/44 males/females) with three-phase CT urography studies was curated for deep learning model development. The three phases for each patient were aligned with an affine registration algorithm. A custom model, coined Residual transformer model for Nephrographic phase CT image synthesis (ResNCT), was developed and implemented with paired inputs of non-contrast and urographic sets of images trained to produce the nephrographic phase images, that were compared with the corresponding ground truth nephrographic phase images. The synthesized images were evaluated with multiple performance metrics, including peak signal to noise ratio (PSNR), structural similarity index (SSIM), normalized cross correlation coefficient (NCC), mean absolute error (MAE), and root mean squared error (RMSE). Results: The ResNCT model successfully generated synthetic nephrographic images from non-contrast and urographic image inputs. With respect to ground truth nephrographic phase images, the images synthesized by the model achieved high PSNR (27.8 $\pm$ 2.7 dB), SSIM (0.88 $\pm$ 0.05), and NCC (0.98 $\pm$ 0.02), and low MAE (0.02 $\pm$ 0.005) and RMSE (0.042 $\pm$ 0.016). Conclusion: The ResNCT model synthesized nephrographic phase CT images with high similarity to ground truth images. The ResNCT model provides a means of eliminating the acquisition of the nephrographic phase with a resultant 33% reduction in radiation dose for CTU examinations.
Comment: 10 pages, 5 Figures,2 Tables
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2405.04629
رقم الأكسشن: edsarx.2405.04629
قاعدة البيانات: arXiv