Symbolic mathematical computing systems have served as a canary in the coal mine of software systems for more than sixty years. They have introduced or have been early adopters of programming language ideas such ideas as dynamic memory management, arbitrary precision arithmetic and dependent types. These systems have the feature of being highly complex while at the same time operating in a domain where results are well-defined and clearly verifiable. These software systems span multiple layers of abstraction with concerns ranging from instruction scheduling and cache pressure up to algorithmic complexity of constructions in algebraic geometry. All of the major symbolic mathematical computing systems include low-level code for arithmetic, memory management and other primitives, a compiler or interpreter for a bespoke programming language, a library of high level mathematical algorithms, and some form of user interface. Each of these parts invokes multiple deep issues. We present some lessons learned from this environment and free flowing opinions on topics including: * Portability of software across architectures and decades; * Infrastructure to embrace and infrastructure to avoid; * Choosing base abstractions upon which to build; * How to get the most out of a small code base; * How developments in compilers both to optimise and to validate code have always been and remain of critical importance, with plenty of remaining challenges; * The way in which individuals including in particular Alan Mycroft who has been able to span from hand-crafting Z80 machine code up to the most abstruse high level code analysis techniques are needed, and * Why it is important to teach full-stack thinking to the next generation.
