Flexibility in noisy cell-to-cell information dynamics

التفاصيل البيبلوغرافية
العنوان: Flexibility in noisy cell-to-cell information dynamics
المؤلفون: Qunbar, Ismail, Vennettilli, Michael, Erez, Amir
سنة النشر: 2024
المجموعة: Physics (Other)
Quantitative Biology
مصطلحات موضوعية: Physics - Biological Physics, Quantitative Biology - Molecular Networks
الوصف: Exchange of molecules allows cells to exchange information. How robust is the information to changes in cell parameters? We use a mapping between the stochastic dynamics of two cells sharing a stimulatory molecule, and parameters akin to an extension of Landau's equilibrium phase transition theory. We show that different single-cell dynamics lead to the same dynamical response -- a flexibility that cells can use. The companion equilibrium Landau model behaves similarly, thereby describing the dynamics of information in a broad class of models with coupled order parameters.
Comment: Main text: 6 pages, 3 figures; Supplement: 2 page, 1 figure
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2407.06556
رقم الأكسشن: edsarx.2407.06556
قاعدة البيانات: arXiv