Document-level Clinical Entity and Relation Extraction via Knowledge Base-Guided Generation

التفاصيل البيبلوغرافية
العنوان: Document-level Clinical Entity and Relation Extraction via Knowledge Base-Guided Generation
المؤلفون: Bhattarai, Kriti, Oh, Inez Y., Abrams, Zachary B., Lai, Albert M.
سنة النشر: 2024
المجموعة: Computer Science
مصطلحات موضوعية: Computer Science - Computation and Language, Computer Science - Artificial Intelligence
الوصف: Generative pre-trained transformer (GPT) models have shown promise in clinical entity and relation extraction tasks because of their precise extraction and contextual understanding capability. In this work, we further leverage the Unified Medical Language System (UMLS) knowledge base to accurately identify medical concepts and improve clinical entity and relation extraction at the document level. Our framework selects UMLS concepts relevant to the text and combines them with prompts to guide language models in extracting entities. Our experiments demonstrate that this initial concept mapping and the inclusion of these mapped concepts in the prompts improves extraction results compared to few-shot extraction tasks on generic language models that do not leverage UMLS. Further, our results show that this approach is more effective than the standard Retrieval Augmented Generation (RAG) technique, where retrieved data is compared with prompt embeddings to generate results. Overall, we find that integrating UMLS concepts with GPT models significantly improves entity and relation identification, outperforming the baseline and RAG models. By combining the precise concept mapping capability of knowledge-based approaches like UMLS with the contextual understanding capability of GPT, our method highlights the potential of these approaches in specialized domains like healthcare.
Comment: Accepted at Association for Computational Linguistics BioNLP 2024
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2407.10021
رقم الأكسشن: edsarx.2407.10021
قاعدة البيانات: arXiv