دورية أكاديمية
أعرض في EDS

Vitamin D and Osteogenesis Imperfecta in Pediatrics

التفاصيل البيبلوغرافية
العنوان: Vitamin D and Osteogenesis Imperfecta in Pediatrics
المؤلفون: Francesco Coccia, Angelo Pietrobelli, Thomas Zoller, Alessandra Guzzo, Paolo Cavarzere, Angelo Fassio, Carl-Erik Flodmark, Davide Gatti, Franco Antoniazzi
المصدر: Pharmaceuticals, Vol 16, Iss 5, p 690 (2023)
بيانات النشر: MDPI AG, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine
LCC:Pharmacy and materia medica
مصطلحات موضوعية: osteogenesis imperfecta, vitamin D, pediatrics, Medicine, Pharmacy and materia medica, RS1-441
الوصف: Osteogenesis Imperfecta (OI) is a heterogeneous group of inherited skeletal dysplasias characterized by bone fragility. The study of bone metabolism, in these disease, is problematic in terms of clinical and genetic variability. The aims of our study were to evaluate the importance of Vitamin D levels in OI bone metabolism, reviewing studies performed on this topic and providing advice reflecting our experience using vitamin D supplementation. A comprehensive review on all English-language articles was conducted in order to analyze the influence of vitamin D in OI bone metabolism in pediatric patients. Reviewing the studies, contradictory data were found on the relationship between 25OH vitamin D levels and bone parameters in OI, and in several studies the baseline levels of 25OH D were below the threshold value of 75 nmol/L. In conclusion, according to the literature and to our experience, we highlight the importance of adequate vitamin D supplementation in children with OI.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1424-8247
Relation: https://www.mdpi.com/1424-8247/16/5/690; https://doaj.org/toc/1424-8247
DOI: 10.3390/ph16050690
URL الوصول: https://doaj.org/article/0072d488d7ea4a9cb9c4b8903b069936
رقم الأكسشن: edsdoj.0072d488d7ea4a9cb9c4b8903b069936
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14248247
DOI:10.3390/ph16050690