دورية أكاديمية
GENETIC POLYMORPHISMS AS THE RISK FACTOR IN THE DEVELOPMENT OF OSTEOARTHRITIS
| العنوان: | GENETIC POLYMORPHISMS AS THE RISK FACTOR IN THE DEVELOPMENT OF OSTEOARTHRITIS |
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| المؤلفون: | S. B. Panina |
| المصدر: | Медицинский вестник Юга России, Vol 0, Iss 2, Pp 13-20 (2014) |
| بيانات النشر: | State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation, 2014. |
| سنة النشر: | 2014 |
| المجموعة: | LCC:Medicine (General) |
| مصطلحات موضوعية: | osteoarthritis, genetic polymorphisms, gwas, candidate genes, matrix metalloproteinases, Medicine (General), R5-920 |
| الوصف: | It’s well-known that osteoarthritis (OA) is a widespread form of degenerative joint disorder that has the significant genetic component. The studies concerning the role of various candidate genes in the OA development are analyzed; much attention is given to the exploration of matrix metalloproteinases, their inhibitors and interleukin genes polymorphisms. The paper describes the results of up-to-date genome-wide association scanning and meta-analyses of polymorphisms associated with osteoarthritis in detail. The paper also considers the problem of the linkage between epigenetic alterations and the susceptibility to OA. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Russian |
| تدمد: | 2219-8075 2618-7876 |
| Relation: | https://www.medicalherald.ru/jour/article/view/165; https://doaj.org/toc/2219-8075; https://doaj.org/toc/2618-7876 |
| DOI: | 10.21886/2219-8075-2014-2-13-20 |
| URL الوصول: | https://doaj.org/article/dc00889f5fb24c7d8900f485a7bab1b2 |
| رقم الأكسشن: | edsdoj.00889f5fb24c7d8900f485a7bab1b2 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22198075 26187876 |
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| DOI: | 10.21886/2219-8075-2014-2-13-20 |