Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics

التفاصيل البيبلوغرافية
العنوان:	Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics
المؤلفون:	Nicolas Bertrand, Philippe Grenier, Morteza Mahmoudi, Eliana M. Lima, Eric A. Appel, Flavio Dormont, Jong-Min Lim, Rohit Karnik, Robert Langer, Omid C. Farokhzad
المصدر:	Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
بيانات النشر:	Nature Portfolio, 2017.
سنة النشر:	2017
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Understanding the interaction between nanoparticles and biomolecules is crucial for improving current drug-delivery systems. Here, the authors shed light on the essential role of the surface and other physicochemical properties of a library of nanoparticles on their in vivo pharmacokinetics.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/s41467-017-00600-w
URL الوصول:	https://doaj.org/article/00dc4fa9069d4166b50ad9376daec172
رقم الأكسشن:	edsdoj.00dc4fa9069d4166b50ad9376daec172
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-017-00600-w