دورية أكاديمية
Compliance and feasibility of the ketoacid-supplemented very low protein diet in patients with CKD
| العنوان: | Compliance and feasibility of the ketoacid-supplemented very low protein diet in patients with CKD |
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| المؤلفون: | Eduardo Lorca-Herrera, Verònica Soto, Macarena Arancibia, Maria R. Berlanga, Francisca Peña, Caterina Tiscornia, Magdalena Whittaker, Gonzalo Correa, Jefferson Hidalgo, Alvaro Morales, Alvaro Rios, Daniel Bunout |
| المصدر: | Nefrología Latinoamericana, Vol 19, Iss 2 (2022) |
| بيانات النشر: | Permanyer, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Special situations and conditions |
| مصطلحات موضوعية: | Renal failure. Ketoacids. Dietary proteins., Special situations and conditions, RC952-1245 |
| الوصف: | Objective: To assess the effects of a very low protein diet supplemented with ketoacids on urinary urea nitrogen excretion and kidney function tests, in a randomized controlled clinical trial. Material and methods: Patients with stage 4-5 of CKD treated at a nephrology unit of a general hospital, were randomized to receive Ketosteril® 1 tablet per 5 kg/body weight day and a very low protein diet providing 0.3 g/kg of proteins or only a low protein diet providing 0.6 g/kg of proteins (control group). At baseline and after 16 weeks of treatment, fasting blood, 24 h and spot urine samples were collected. Results: Eighty-nine patients were randomized to the control and 93 to the ketoacids group. Fifty-four and 71 patients in each group, respectively, completed the treatment. Patients in the ketoacids group experienced a significantly higher reduction in urinary urea nitrogen and urine phosphorus excretion. Specifically, serum creatinine and cystatin C, did not change significantly. Conclusions: Patients receiving ketoacids had a greater reduction in urine urea nitrogen excretion during the treatment period which reflects good compliance with the very low protein diet. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Spanish; Castilian |
| تدمد: | 2444-9032 |
| Relation: | https://www.nefrologialatinoamericana.com/frame_esp.php?id=80; https://doaj.org/toc/2444-9032 |
| DOI: | 10.24875/NEFRO.22000017 |
| URL الوصول: | https://doaj.org/article/a0132e88b1544f33a9a9d405abf92002 |
| رقم الأكسشن: | edsdoj.0132e88b1544f33a9a9d405abf92002 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 24449032 |
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| DOI: | 10.24875/NEFRO.22000017 |