دورية أكاديمية
Intra-Seasonal Initiation of the SQ-Standardised Grass Allergy Immunotherapy Tablet Routinely Applied by Allergy Specialists and General Practitioners with Experience in Treatment of Allergy: A Non-Interventional Observational Study
| العنوان: | Intra-Seasonal Initiation of the SQ-Standardised Grass Allergy Immunotherapy Tablet Routinely Applied by Allergy Specialists and General Practitioners with Experience in Treatment of Allergy: A Non-Interventional Observational Study |
|---|---|
| المؤلفون: | Jan-Alexander Schwab, Hendrik Wolf, Jörg Schnitker, Eike Wüstenberg |
| المصدر: | Pulmonary Therapy, Vol 4, Iss 1, Pp 45-57 (2018) |
| بيانات النشر: | Adis, Springer Healthcare, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Diseases of the respiratory system |
| مصطلحات موضوعية: | Allergy immunotherapy tablet, GRAZAX®, In season, Phleum pratense, Rhinoconjunctivitis, Sublingual immunotherapy, Diseases of the respiratory system, RC705-779 |
| الوصف: | Abstract Introduction Intra-seasonal start of treatment with the SQ® grass sublingual immunotherapy(SLIT) tablet (GRAZAX®, ALK, Denmark) has been previously demonstrated to be well-tolerated. The objective of our study was to investigate the tolerability of intra-seasonal start of treatment comparing patients treated by allergists and general practitioners experienced in treatment of allergy (GPs). Methods In a non-interventional, open-label, observational study, data on intra-seasonal start with the SQ® grass SLIT tablet were recorded in patients treated by allergists and GPs in Germany. Adverse events (AEs) were recorded by the physicians at first administration and during the 1–3-month observation period. The tablets taken and any AEs were recorded by the patients in diaries for the first 14 days. Results Treatment with the SQ® grass SLIT tablet was started in 198 patients, and in 179 intra-seasonal (allergists: 140, GPs: 39) and 19 post-seasonal; average treatment period was 47 days. AEs related to intra-seasonal start were reported in 43.6% of patients; no relevant differences between allergists and GPs were observed. In the subgroup of GPs, patients were younger (p = 0.0191), had more frequently asthma (p = 0.0043), more patients used symptomatic medication in the previous pollen season (p = 0.0198) and were more frequently treated for other diseases (p = 0.0467). In the allergists subgroup, more diagnostic allergy tests were applied (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2364-1754 2364-1746 |
| Relation: | https://doaj.org/toc/2364-1754; https://doaj.org/toc/2364-1746 |
| DOI: | 10.1007/s41030-018-0050-1 |
| URL الوصول: | https://doaj.org/article/013b8db09e2042419d65b56c45fbde94 |
| رقم الأكسشن: | edsdoj.013b8db09e2042419d65b56c45fbde94 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 23641754 23641746 |
|---|---|
| DOI: | 10.1007/s41030-018-0050-1 |