دورية أكاديمية
A Pilot Study of FDG-PET/CT in Polycythemia Vera Using Global Analysis Techniques
| العنوان: | A Pilot Study of FDG-PET/CT in Polycythemia Vera Using Global Analysis Techniques |
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| المؤلفون: | Cyrus Ayubcha, Hitomi Hosoya, Siavash Mehdizadeh Seraj, Mahdi Zirakchian Zadeh, Thomas Werner, Abass Alavi |
| المصدر: | Asia Oceania Journal of Nuclear Medicine and Biology, Vol 8, Iss 1, Pp 64-68 (2020) |
| بيانات النشر: | Mashhad University of Medical Sciences, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Medical physics. Medical radiology. Nuclear medicine LCC:Biology (General) |
| مصطلحات موضوعية: | polycythemia vera, fdg-pet/ct, myeloproliferative neoplasm, non-invasive procedure, global analysis, Medical physics. Medical radiology. Nuclear medicine, R895-920, Biology (General), QH301-705.5 |
| الوصف: | Objective(s): Functional imaging presents a non-invasive process that may capture the hyper-metabolic nature of red bone marrow in myeloproliferative neoplasms, such as polycythemia vera (PV). Methods: This study analyzed the FDG-PET/CT scans (n=12) of six patients diagnosed with PV and six age-sex matched controls using a quantitative global analysis methodology. Results: All PV patients had elevated activities in the bone marrow of each skeletal structure as compared to matched controls with respect to mean standardized uptake value (femoral neck p=0.01, lumbar spine p=0.02, pelvis p=0.002, sternum p=0.04). Notable variations in splenic uptake were observed among the treated and untreated PV patients. Conclusion: Our study exemplifies the potential utility of PET in reflecting hyperactive bone marrow activity related to PV. Future studies may further substantiate and elaborate on the use of PET-derived metabolic data in PV. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2322-5718 2322-5726 |
| Relation: | http://aojnmb.mums.ac.ir/article_14016_10cdf2736b2993adf6af01139dcfc33d.pdf; https://doaj.org/toc/2322-5718; https://doaj.org/toc/2322-5726 |
| DOI: | 10.22038/aojnmb.2019.41192.1278 |
| URL الوصول: | https://doaj.org/article/a01c857237c54c4ca44dfa8740d9a82c |
| رقم الأكسشن: | edsdoj.01c857237c54c4ca44dfa8740d9a82c |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23225718 23225726 |
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| DOI: | 10.22038/aojnmb.2019.41192.1278 |