دورية أكاديمية
Association Analysis to Copy Number Variation (CNV) of Opn4 Gene with Growth Traits of Goats
| العنوان: | Association Analysis to Copy Number Variation (CNV) of Opn4 Gene with Growth Traits of Goats |
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| المؤلفون: | LiJuan Li, Peng Yang, ShuYue Shi, ZiJing Zhang, QiaoTing Shi, JiaWei Xu, Hua He, ChuZhao Lei, ErYao Wang, Hong Chen, YongZhen Huang |
| المصدر: | Animals, Vol 10, Iss 3, p 441 (2020) |
| بيانات النشر: | MDPI AG, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Veterinary medicine LCC:Zoology |
| مصطلحات موضوعية: | copy number variation (cnvs), opn4 gene, growth traits, guizhou goat, Veterinary medicine, SF600-1100, Zoology, QL1-991 |
| الوصف: | Extensive research has been carried out regarding the correlation between the growth traits of livestock and genetic polymorphisms, including single nucleotide polymorphisms and copy number variations (CNV). The purpose of this study was to analyze the CNV and its genetic effects of the Opn4 gene in 284 Guizhou goats (Guizhou black goat: n = 186, Guizhou white goat: n = 98). We used qPCR to detect the CNV of the Opn4 gene in Guizhou goats, and the classification results were correlated with the corresponding individual growth traits by SPSS software. The results showed that the Opn4 gene had a superior effect on growth traits with multiple copy variants in Guizhou black goats, and there was a significant correlation between copy number variation sites and body length traits. Contrary to the former conclusion, in Guizhou white goats, individuals with the Normal copy number type showed superior growth traits and copy number variant sites were significantly associated with body weight traits. Therefore, the CNV of the Opn4 gene can be used as a candidate molecular genetic marker to improve goat growth traits, speeding up the breeding process of goat elite varieties. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2076-2615 10030441 |
| Relation: | https://www.mdpi.com/2076-2615/10/3/441; https://doaj.org/toc/2076-2615 |
| DOI: | 10.3390/ani10030441 |
| URL الوصول: | https://doaj.org/article/d01dd2ba9cfb4fe7b5eca1084c9e4233 |
| رقم الأكسشن: | edsdoj.01dd2ba9cfb4fe7b5eca1084c9e4233 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20762615 10030441 |
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| DOI: | 10.3390/ani10030441 |