دورية أكاديمية
Successful treatment of Rhizopus arrhizus rhino-orbital-cerebral mucormycosis with isavuconazole salvage therapy following extensive debridement
| العنوان: | Successful treatment of Rhizopus arrhizus rhino-orbital-cerebral mucormycosis with isavuconazole salvage therapy following extensive debridement |
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| المؤلفون: | R.P. Miller, L. Farrugia, J. Leask, K. Khalsa, N. Khanna, L. Melia |
| المصدر: | Medical Mycology Case Reports, Vol 32, Iss , Pp 39-42 (2021) |
| بيانات النشر: | Elsevier, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine (General) LCC:Biology (General) |
| مصطلحات موضوعية: | Rhino-orbital-cerebral mucormycosis, Diabetes mellitus, Isavuconazole, Rhizopus arrhizus, Medicine (General), R5-920, Biology (General), QH301-705.5 |
| الوصف: | A 61-year old lady with poorly-controlled type 2 diabetes mellitus was diagnosed with rhino-orbital-cerebral mucormycosis following presentation with sinusitis, ophthalmoplegia, proptosis and facial numbness. She was treated successfully with aggressive surgical intervention including orbital exenteration, accompanied by anti-fungal therapy with liposomal amphotericin B and posaconazole, followed by isavuconazole as salvage therapy. We discuss the challenges around optimising antifungal therapy of this lethal infection in the context of hepatic and renal toxicity. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2211-7539 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2211753921000142; https://doaj.org/toc/2211-7539 |
| DOI: | 10.1016/j.mmcr.2021.03.005 |
| URL الوصول: | https://doaj.org/article/0212a66c49f7489ba3fe0743bc3be33f |
| رقم الأكسشن: | edsdoj.0212a66c49f7489ba3fe0743bc3be33f |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22117539 |
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| DOI: | 10.1016/j.mmcr.2021.03.005 |