دورية أكاديمية
Clinical, Echocardiographic, and Electrocardiographic Predictors of Persistent Atrial Fibrillation after Dual-Chamber Pacemaker Implantation: An Integrated Scoring Model Approach.
العنوان: | Clinical, Echocardiographic, and Electrocardiographic Predictors of Persistent Atrial Fibrillation after Dual-Chamber Pacemaker Implantation: An Integrated Scoring Model Approach. |
---|---|
المؤلفون: | Min Soo Cho, Jun Kim, Ju Hyeon Kim, Minsu Kim, Ji Hyun Lee, You Mi Hwang, Uk Jo, Gi-Byoung Nam, Kee-Joon Choi, You-Ho Kim |
المصدر: | PLoS ONE, Vol 11, Iss 8, p e0160422 (2016) |
بيانات النشر: | Public Library of Science (PLoS), 2016. |
سنة النشر: | 2016 |
المجموعة: | LCC:Medicine LCC:Science |
مصطلحات موضوعية: | Medicine, Science |
الوصف: | Persistent atrial fibrillation (PeAF) predictors after dual-chamber pacemaker (PM) implantation remain unclear. We sought to determine these predictors and establish an integrated scoring model. Data were retrospectively reviewed for 649 patients (63.8 ± 12.3 years, 48.6% male, mean CHA2DS2-VASC score 2.7 ± 2.0) undergoing dual-chamber PM implantation. PeAF was defined as documented AF on two consecutive electrocardiograms acquired ≥7 days apart. During a 7.1-year median follow-up (interquartile range 4.5-10.1 years), 67 (10.3%) patients had PeAF. Multivariable analysis showed the following independent predictors of future PeAF: ischemic stroke or transient ischemic accident history (hazard ratio [HR] 2.03, 95% confidence interval [CI] 1.03-3.50, p = 0.040), atrial fibrillation/flutter history (HR 1.80, 95% CI 1.01-3.20, p = 0.046), sinus node disease (HR 2.24, 95% CI 1.16-4.35, p = 0.016), left atrial enlargement (>45 mm, HR 2.14, 95% CI 1.26-3.63, p = 0.005), and time in automatic mode switching >1% at first follow-up interrogation (HR 2.58, 95% CI 1.51-4.42, p < 0.001). An integrated scoring model combining these predictors showed good discrimination performance at the seven-year follow-up. (C-statistic 0.716, 95% CI 0.629-0.802, p < 0.001). Significantly greater seven-year PeAF incidences were seen in patients with higher scores (2-5) than in those with lower scores (0-1) (22.8% ± 3.8% vs. 5.3% ± 1.7%, p < 0.001). In conclusion, an integrated scoring model combining clinical, echocardiographic, and electrocardiographic characteristics is useful for predicting future PeAF in patients with a dual-chamber PM. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1932-6203 53572408 |
Relation: | http://europepmc.org/articles/PMC4968832?pdf=render; https://doaj.org/toc/1932-6203 |
DOI: | 10.1371/journal.pone.0160422 |
URL الوصول: | https://doaj.org/article/d02177e53572408684efed284210c41b |
رقم الأكسشن: | edsdoj.02177e53572408684efed284210c41b |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 19326203 53572408 |
---|---|
DOI: | 10.1371/journal.pone.0160422 |