دورية أكاديمية
Prevalence of hypothalamo pituitary dysfunction in patients of traumatic brain injury
| العنوان: | Prevalence of hypothalamo pituitary dysfunction in patients of traumatic brain injury |
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| المؤلفون: | K. V. S. Hari Kumar, M N Swamy, M A Khan |
| المصدر: | Indian Journal of Endocrinology and Metabolism, Vol 20, Iss 6, Pp 772-778 (2016) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | Central hypothyroidism, head injury, hypogonadism, hypopituitarism, traumatic brain injury, Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Background: Traumatic brain injury (TBI) is common in young soldiers of armed forces leading to significant morbidity and mortality. We studied the prevalence of hypopituitarism following TBI and its association with trauma severity. Materials and Methods: We conducted a 12-month prospective study of 56 TBI patients for the presence of hormonal dysfunction. Hormonal parameters were estimated during the early phase (0–10 days posttraumatically) and after 6 and 12 months. Dynamic testing was done when required, and the results were analyzed by appropriate statistical methods. Results: Hormonal dysfunction was seen in 39 of the 56 (70%) patients at initial assessment. Persisting pituitary deficiencies are seen in 7 and 8 patients at the end of 6 months and 12 months, respectively. Hypogonadotropic hypogonadism, hypothyroidism, and growth hormone deficiency are the most common diagnoses. Initial severe TBI and plurihormonal involvement predicted the long-term hypopituitarism. Conclusion: Early hypopituitarism was common in severe TBI, but recovers in majority. Evaluation for the occult pituitary dysfunction is required during the rehabilitation of TBI patients. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2230-8210 |
| Relation: | http://www.ijem.in/article.asp?issn=2230-8210;year=2016;volume=20;issue=6;spage=772;epage=778;aulast=Hari; https://doaj.org/toc/2230-8210 |
| DOI: | 10.4103/2230-8210.192917 |
| URL الوصول: | https://doaj.org/article/ada02594f2524ac4a74a034a623f85d2 |
| رقم الأكسشن: | edsdoj.02594f2524ac4a74a034a623f85d2 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22308210 |
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| DOI: | 10.4103/2230-8210.192917 |