دورية أكاديمية
Antimicrobial Susceptibility in Respiratory Pathogens and Farm and Animal Variables in Weaned California Dairy Heifers: Logistic Regression and Bayesian Network Analyses
| العنوان: | Antimicrobial Susceptibility in Respiratory Pathogens and Farm and Animal Variables in Weaned California Dairy Heifers: Logistic Regression and Bayesian Network Analyses |
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| المؤلفون: | Brittany L. Morgan Bustamante, Munashe Chigerwe, Beatriz Martínez-López, Sharif S. Aly, Gary McArthur, Wagdy R. ElAshmawy, Heather Fritz, Deniece R. Williams, John Wenz, Sarah Depenbrock |
| المصدر: | Antibiotics, Vol 13, Iss 1, p 50 (2024) |
| بيانات النشر: | MDPI AG, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Therapeutics. Pharmacology |
| مصطلحات موضوعية: | Bayesian network analysis, Pasteurella multocida, Mannheimia haemolytica, Histophilus somni, antibiotic, antimicrobial drug, Therapeutics. Pharmacology, RM1-950 |
| الوصف: | Weaned dairy heifers are a relatively understudied production group. Bovine respiratory disease (BRD) is the most common cause of antimicrobial drug (AMD) use, morbidity, and mortality in this production group. The study of antimicrobial resistance (AMR) is complicated because many variables that may affect AMR are related. This study generates hypotheses regarding the farm- and animal-level variables (e.g., vaccination, lane cleaning, and AMD use practices) that may be associated with AMR in respiratory isolates from weaned dairy heifers. A cross-sectional study was performed using survey data and respiratory isolates (Pasteurella multocida, Mannheimia haemolytica, and Histophilus somni) collected from 341 weaned dairy heifers on six farms in California. Logistic regression and Bayesian network analyses were used to evaluate the associations between farm- and animal-level variables with minimum inhibitory concentration (MIC) classification of respiratory isolates against 11 AMDs. Farm-level variables associated with MIC classification of respiratory isolates included the number of source farms of a calf-rearing facility, whether the farm practiced onsite milking, the use of lagoon water for flush lane cleaning, and respiratory and pinkeye vaccination practices. Animal-level variables associated with a MIC classification included whether the calf was BRD-score-positive and time since the last phenicol treatment. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 13010050 2079-6382 |
| Relation: | https://www.mdpi.com/2079-6382/13/1/50; https://doaj.org/toc/2079-6382 |
| DOI: | 10.3390/antibiotics13010050 |
| URL الوصول: | https://doaj.org/article/02c2cbb79e754832b9a3980dff805e0c |
| رقم الأكسشن: | edsdoj.02c2cbb79e754832b9a3980dff805e0c |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 13010050 20796382 |
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| DOI: | 10.3390/antibiotics13010050 |