دورية أكاديمية

Does daily co-administration of letrozole and gonadotropins during ovarian stimulation improve IVF outcome?

التفاصيل البيبلوغرافية
العنوان: Does daily co-administration of letrozole and gonadotropins during ovarian stimulation improve IVF outcome?
المؤلفون: Jigal Haas, Rawad Bassil, Jim Meriano, Nivin Samara, Eran Barzilay, Noa Gonen, Robert F. Casper
المصدر: Reproductive Biology and Endocrinology, Vol 15, Iss 1, Pp 1-5 (2017)
بيانات النشر: BMC, 2017.
سنة النشر: 2017
المجموعة: LCC:Gynecology and obstetrics
LCC:Reproduction
مصطلحات موضوعية: Letrozole, Androgen, Aromatase inhibitor, Gynecology and obstetrics, RG1-991, Reproduction, QH471-489
الوصف: Abstract Background For the last year we have been treating normal responders with gonadotropins and letrozole during the whole stimulation in order to improve response to FSH by increasing the intrafollicular androgen concentration, and to reduce circulating estrogen concentrations. The aim of this study was to compare the IVF outcome of normal responders treated with letrozole and gonadotropins during ovarian stimulation with patients treated with gonadotropins only. Methods A single centre retrospective cohort study of 174 patients (87 in each group). Results The age of the patients was comparable between the groups. Estradiol levels were significantly higher in the control group (6760 pmol/L vs. 2420 pmol/L respectively, p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1477-7827
Relation: http://link.springer.com/article/10.1186/s12958-017-0288-8; https://doaj.org/toc/1477-7827
DOI: 10.1186/s12958-017-0288-8
URL الوصول: https://doaj.org/article/c02fdfdde812480b8aa080cbfc98ce66
رقم الأكسشن: edsdoj.02fdfdde812480b8aa080cbfc98ce66
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14777827
DOI:10.1186/s12958-017-0288-8