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Nimbolide B and Nimbic Acid B, Phytotoxic Substances in Neem Leaves with Allelopathic Activity

التفاصيل البيبلوغرافية
العنوان: Nimbolide B and Nimbic Acid B, Phytotoxic Substances in Neem Leaves with Allelopathic Activity
المؤلفون: Hisashi Kato-Noguchi, Md Abdus Salam, Osamu Ohno, Kiyotake Suenaga
المصدر: Molecules, Vol 19, Iss 6, Pp 6929-6940 (2014)
بيانات النشر: MDPI AG, 2014.
سنة النشر: 2014
المجموعة: LCC:Organic chemistry
مصطلحات موضوعية: allelopathy, Azadirachta indica, bioactive compound, growth inhibitor, medicinal plant, phytotoxicity, Organic chemistry, QD241-441
الوصف: Neem (Azadirachta indica) has been widely used as a traditional medicine and several bioactive compounds have been isolated from this species, but to date no potent allelopathic active substance has been reported. Therefore, we investigated possible allelopathic property and phytotoxic substances with allelopathic activity in neem. An aqueous methanol extract of neem leaves inhibited the growth of roots and shoots of cress, lettuce, alfalfa, timothy, crabgrass, ryegrass, barnyard grass and jungle rice. The extracts were then purified by several chromatographic runs while monitoring the inhibitory activity and two phytotoxic substances were isolated. The chemical structures of the two substances were determined by spectral data to correspond to novel compounds, nimbolide B (1) and nimbic acid B (2). Nimbolide B inhibited the growth of cress and barnyard grass at concentrations greater than 0.1‒3.0 μM. Nimbic acid B inhibited the growth of cress and barnyard grass at concentrations greater than 0.3–1.0 μM. These results suggest that nimbolide B and nimbic acid B may contribute to the allelopathic effects caused by neem leaves.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1420-3049
19066929
48402249
Relation: http://www.mdpi.com/1420-3049/19/6/6929; https://doaj.org/toc/1420-3049
DOI: 10.3390/molecules19066929
URL الوصول: https://doaj.org/article/e0301ae01b9a46c484022492884c019f
رقم الأكسشن: edsdoj.0301ae01b9a46c484022492884c019f
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14203049
19066929
48402249
DOI:10.3390/molecules19066929