دورية أكاديمية
Use of transcutaneous electrical acupoint stimulation in pulmonary surgery for patients with tuberculosis
العنوان: | Use of transcutaneous electrical acupoint stimulation in pulmonary surgery for patients with tuberculosis |
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المؤلفون: | Lu-lu Xu, Wen-sheng Zhao, Lang-ping Li, Xin-dan Du |
المصدر: | Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Vol 27, Iss , Pp 100298- (2022) |
بيانات النشر: | Elsevier, 2022. |
سنة النشر: | 2022 |
المجموعة: | LCC:Diseases of the respiratory system LCC:Infectious and parasitic diseases |
مصطلحات موضوعية: | Transcutaneous electrical acupoint stimulation (TEAS), Tuberculosis, One lung ventilation (OLV), Inflammatory mediators, Lymphocyte subsets, Diseases of the respiratory system, RC705-779, Infectious and parasitic diseases, RC109-216 |
الوصف: | Objective: This study aimed to analyze the effects of transcutaneous electrical acupoint stimulation (TEAS) on the immune function in patients with pulmonary tuberculosis (PT) and the inflammatory response following one-lung ventilation surgery by comparing the levels of inflammatory mediators, such as tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), and interleukin 8 (IL-8); T lymphocyte subsets, including CD3+, CD4+, CD8+, and CD4+/CD8+ cells; and natural killer cells (NK cells). Methods: We randomly divided 62 patients who underwent general anesthesia for thoracotomy into two groups: TEAS and sham TEAS. Patients in the TEAS group underwent bilateral acupoint electrical stimulation at the Hou-Xi, Zhi-Gou, Nei-Guan, and He-Gu acupoints from 30 min before anesthesia induction until the end of surgery. TEAS was continuously maintained throughout the procedure with a dilatational wave at 2/100 Hz. Those in the sham TEAS group underwent the same management but without stimulation, and the anesthesia induction and maintenance methods were the same in both groups. Venous blood was drawn to monitor inflammatory mediators and lymphocyte subsets before anesthesia induction and 5 days after the surgery. Results: There was no statistical difference in the general conditions between the two groups (P > 0.05). Before anesthesia induction, the levels of inflammatory factors (IL-6, IL-8, and TNF-α), lymphocyte subsets (CD3+, CD4+, and CD4+/CD8+), and NK cells did not statistically differ between the two groups (P > 0.05). Compared to the sham TEAS group, the levels of IL-6, IL-8, TNF-α, and CD8+ were lower in the TEAS group, while those of CD3+, CD4+, CD4+/CD8+, and NK cells were higher; however, only the change in TNF-α was significant (P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2405-5794 |
Relation: | http://www.sciencedirect.com/science/article/pii/S2405579422000031; https://doaj.org/toc/2405-5794 |
DOI: | 10.1016/j.jctube.2022.100298 |
URL الوصول: | https://doaj.org/article/03dcb7fe0244452dad9265370f02dc88 |
رقم الأكسشن: | edsdoj.03dcb7fe0244452dad9265370f02dc88 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 24055794 |
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DOI: | 10.1016/j.jctube.2022.100298 |