دورية أكاديمية

Metastasectomy for extracalvarial renal cell carcinoma

التفاصيل البيبلوغرافية
العنوان: Metastasectomy for extracalvarial renal cell carcinoma
المؤلفون: Rahim Abo Kasem, Karan Joseph, Adnan Shaik, Angela Downes, M. Burhan Janjua
المصدر: Clinical Case Reports, Vol 12, Iss 6, Pp n/a-n/a (2024)
بيانات النشر: Wiley, 2024.
سنة النشر: 2024
المجموعة: LCC:Medicine
LCC:Medicine (General)
مصطلحات موضوعية: extracalvarial metastasis, metastatic renal cell carcinoma, preoperative embolization, surgical resection, titanium cranioplasty, Medicine, Medicine (General), R5-920
الوصف: Key Clinical Message Palliative surgical resection of extra‐calvarial metastatic lesions from renal cell tumors is crucial for controlling metastatic spread, improving quality of life, and preventing associated morbidity. Careful surgical planning, including selective preoperative embolization and controlled resection around critical structures such as the sagittal sinus, is essential for successful outcomes. Cranioplasty with Titanium mesh and bone cement post‐resection can provide symptomatic relief, better cosmesis, and overall improved quality of life. Abstract Renal cell carcinomas are aggressive tumors with distant systemic disease. The calvarium appears to be an unusual and rare site for distant metastasis. The treatment modalities are challenging and out of the normal realm for the management of these tumors. We report a case of a 63‐year‐old woman with a previous history of nephrectomy who presented with symptoms of severe headaches, and swelling of bi‐frontal and bi‐parietal scalp regions due to multifocal extracalvarial disease. Preoperative bilateral superficial temporal artery embolization was performed to control the intraoperative bleeding. Surgical technique has been described with the critical steps involved, and a literature review has been conducted. Palliative tumor resection surgery was performed to improve the patient's quality of life as well as to confirm the histopathological diagnosis. Gross total resection of the extracalvarial metastatic tumor was achieved. Biopsy confirmed renal cell tumor with the clear cell subtype. The patient recovered well from her surgery with slow healing of the scalp wound. At 6‐month follow‐up, no recurrence of the extracalvarial disease was observed on serial imaging. Extracalvarial metastasis is a rare presentation in renal cell carcinoma. Considering the inherent radioresistant nature of the tumor, palliative surgical resection can be offered to control the metastatic spread, relieve agonizing pain symptoms, and to improve the quality of life. Preoperative embolization helps to decrease intraoperative blood loss. Moreover, palliative surgical resection of extracalvarial diseases helps to treat the metastasis as well as avoiding the associated morbidity that may occur if left untreated.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2050-0904
Relation: https://doaj.org/toc/2050-0904
DOI: 10.1002/ccr3.8967
URL الوصول: https://doaj.org/article/044c9e8a6cd04d2eb1b65f8bb7127a75
رقم الأكسشن: edsdoj.044c9e8a6cd04d2eb1b65f8bb7127a75
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20500904
DOI:10.1002/ccr3.8967