دورية أكاديمية

Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera

التفاصيل البيبلوغرافية
العنوان: Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera
المؤلفون: Marslin G, Selvakesavan RK, Franklin G, Sarmento B, Dias ACP
المصدر: International Journal of Nanomedicine, Vol 2015, Iss default, Pp 5955-5963 (2015)
بيانات النشر: Dove Medical Press, 2015.
سنة النشر: 2015
المجموعة: LCC:Medicine (General)
مصطلحات موضوعية: Medicine (General), R5-920
الوصف: Gregory Marslin,1 Rajendran K Selvakesavan,1 Gregory Franklin,1 Bruno Sarmento,2,3 Alberto CP Dias11Centre for the Research and Technology of Agro-Environment and Biological Sciences (CITAB-UM), AgroBioPlant Group, Department of Biology, University of Minho, Braga, Portugal; 2Instituto de Engenharia Biomédica (INEB), University of Porto, Porto, Portugal; 3CESPU, Instituto Universitário de Ciências da Saúde, Gandra, PortugalAbstract: We report on the antimicrobial activity of a cream formulation of silver nanoparticles (AgNPs), biosynthesized using Withania somnifera extract. Aqueous extracts of leaves promoted efficient green synthesis of AgNPs compared to fruits and root extracts of W. somnifera. Biosynthesized AgNPs were characterized for their size and shape by physical-chemical techniques such as UV-visible spectroscopy, laser Doppler anemometry, transmission electron microscopy, scanning electron microscopy, atomic force microscopy, X-ray diffraction, and X-ray energy dispersive spectroscopy. After confirming the antimicrobial potential of AgNPs, they were incorporated into a cream. Cream formulations of AgNPs and AgNO3 were prepared and compared for their antimicrobial activity against human pathogens (Staphylococcus aureus, Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli, and Candida albicans) and a plant pathogen (Agrobacterium tumefaciens). Our results show that AgNP creams possess significantly higher antimicrobial activity against the tested organisms.Keywords: Withania somnifera, green synthesis, silver nanoparticles cream, antimicrobial activity
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1178-2013
Relation: https://www.dovepress.com/antimicrobial-activity-of-cream-incorporated-with-silver-nanoparticles-peer-reviewed-article-IJN; https://doaj.org/toc/1178-2013
URL الوصول: https://doaj.org/article/047a4785979a47389b6602a4f3dae1f7
رقم الأكسشن: edsdoj.047a4785979a47389b6602a4f3dae1f7
قاعدة البيانات: Directory of Open Access Journals