دورية أكاديمية
Role of α1‐blockers in the current management of hypertension
| العنوان: | Role of α1‐blockers in the current management of hypertension |
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| المؤلفون: | Hua Li, Ting‐Yan Xu, Yan Li, Yook‐Chin Chia, Peera Buranakitjaroen, Hao‐Min Cheng, Minh Van Huynh, Guru Prasad Sogunuru, Jam Chin Tay, Tzung‐Dau Wang, Kazuomi Kario, Ji‐Guang Wang |
| المصدر: | The Journal of Clinical Hypertension, Vol 24, Iss 9, Pp 1180-1186 (2022) |
| بيانات النشر: | Wiley, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | benign prostatic hyperplasia, hypertension, primary aldosteronism screen, resistant hypertension, α1‐blocker, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Abstract There is emerging evidence that α1‐blockers can be safely used in the treatment of hypertension. These drugs can be used in almost all hypertensive patients for blood pressure control. However, there are several special indications. Benign prostatic hyperplasia is a compelling indication of α1‐blockers, because of the dual treatment effect on both high blood pressure and lower urinary tract symptoms. Many patients with resistant hypertension would require α1‐blockers as add‐on therapy. Primary aldosteronism screen is a rapidly increasing clinical demand in the management of hypertension, where α1‐blockers are useful for blood pressure control in the preparation for the measurement of plasma aldosterone and renin. Nonetheless, α1‐blockers have to be used under several considerations. Among the currently available agents, only long‐acting α1‐blockers, such as doxazosin gastrointestinal therapeutic system 4–8 mg daily and terazosin 2–4 mg daily, should be chosen. Orthostatic hypotension is a concern with the use of α1‐blockers especially in the elderly, and requires careful initial bedtime dosing and avoiding overdosing. Fluid retention is potentially also a concern, which may be overcome by combining an α1‐blocker with a diuretic. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1751-7176 1524-6175 |
| Relation: | https://doaj.org/toc/1524-6175; https://doaj.org/toc/1751-7176 |
| DOI: | 10.1111/jch.14556 |
| URL الوصول: | https://doaj.org/article/04977f20b17f4124ab48cbf0d0f03bf3 |
| رقم الأكسشن: | edsdoj.04977f20b17f4124ab48cbf0d0f03bf3 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17517176 15246175 |
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| DOI: | 10.1111/jch.14556 |