دورية أكاديمية
Recent advances in anti-inflammation via AMPK activation
العنوان: | Recent advances in anti-inflammation via AMPK activation |
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المؤلفون: | Yihua Xu, Lan Bai, Xinwei Yang, Jianli Huang, Jie Wang, Xianbo Wu, Jianyou Shi |
المصدر: | Heliyon, Vol 10, Iss 13, Pp e33670- (2024) |
بيانات النشر: | Elsevier, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Science (General) LCC:Social sciences (General) |
مصطلحات موضوعية: | AMPK, Inflammation, SIRT, Inflammasome, NF-κB, Treatment, Science (General), Q1-390, Social sciences (General), H1-99 |
الوصف: | Inflammation is a complex physiological phenomenon, which is the body's defensive response, but abnormal inflammation can have adverse effects, and many diseases are related to the inflammatory response. AMPK, as a key sensor of cellular energy status, plays a crucial role in regulating cellular energy homeostasis and glycolipid metabolism. In recent years, the anti-inflammation effect of AMPK and related signalling cascade has begun to enter everyone's field of vision – not least the impact on metabolic diseases. A great number of studies have shown that anti-inflammatory drugs work through AMPK and related pathways.Herein, this article summarises recent advances in compounds that show anti-inflammatory effects by activating AMPK and attempts to comment on them. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2405-8440 |
Relation: | http://www.sciencedirect.com/science/article/pii/S2405844024097019; https://doaj.org/toc/2405-8440 |
DOI: | 10.1016/j.heliyon.2024.e33670 |
URL الوصول: | https://doaj.org/article/d04c05b8ba854b79b37512a98fa01f1e |
رقم الأكسشن: | edsdoj.04c05b8ba854b79b37512a98fa01f1e |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 24058440 |
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DOI: | 10.1016/j.heliyon.2024.e33670 |